Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals

Summary

Recent research has identified the following withdrawal symptoms to be associated with abruptly stopping marijuana use: anxiety, irritability, bodily aches and pains, and difficulty sleeping. These symptoms resemble those of both depression and nicotine withdrawal, suggesting that a similar treatment drug may be useful. This study will evaluate the effectiveness of two antidepressant drugs, bupropion and nefazodone, in reducing withdrawal symptoms in marijuana dependent individuals.

Timeline

Start

2000-09

Primary completion

2004-09

Completion

2004-09

Drugs

Indications