drugset / Trial / NCT00250796
Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular Carcinoma
RandomizedSingle-groupOpen-labelTreatment
Summary
Primary Aim Determine the response rate and time to progression of the combination of thalidomide, interferon, and octreotide in patients with unresectable hepatocellular carcinoma (cancer of the liver that can't be treated surgically). Secondary Aims 1. Determine the toxicity of this combination in this population. 2. Determine the survival of this patient cohort treated with the combination. 3. Determine the percent of patients with hepatocellular carcinoma who have a positive octreotide scan.
Timeline
- Start
- 2000-09
- Primary completion
- 2006-01
- Completion
- 2006-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Octreotide | Peptide | 30 mg | Intramuscular |
| Comparator | Thalidomide | Other / unclassified | 800 mg | Oral |
| Comparator | interferon alfa-2b | Protein / enzyme biologic | — | — |