drugset / Trial / NCT00250796

Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular Carcinoma

NCT00250796

Phase 2 Completed 12 enrolled University of New Mexico
RandomizedSingle-groupOpen-labelTreatment

Summary

Primary Aim Determine the response rate and time to progression of the combination of thalidomide, interferon, and octreotide in patients with unresectable hepatocellular carcinoma (cancer of the liver that can't be treated surgically). Secondary Aims 1. Determine the toxicity of this combination in this population. 2. Determine the survival of this patient cohort treated with the combination. 3. Determine the percent of patients with hepatocellular carcinoma who have a positive octreotide scan.

Timeline

Start
2000-09
Primary completion
2006-01
Completion
2006-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Octreotide Peptide 30 mg Intramuscular
Comparator Thalidomide Other / unclassified 800 mg Oral
Comparator interferon alfa-2b Protein / enzyme biologic

Indications