Experimental Headache Induced by Vasoactive Intestinal Polypeptide

Summary

We hypothesized that infusion of VIP may induce headache in healthy subjects and that VIP induced headache may be associated with dilatation of intra- and extracerebral blood vessels. To test this hypothesis, we performed a double blind placebo controlled crossover study in normal human volunteers and studied the effect on headache and cerebral as well as hemodynamic parameters.

Timeline

Start

2003-12

Primary completion

—

Completion

2004-06

Drugs

Indications