Sorafenib and Temsirolimus in Treating Patients With Unresectable or Metastatic Solid Tumors

Summary

This phase I trial is studying the side effects and best dose of temsirolimus when given together with sorafenib in treating patients with unresectable or metastatic solid tumors. Sorafenib and temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Sorafenib may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving sorafenib together with temsirolimus may kill more tumor cells.

Timeline

Start

2005-09

Primary completion

2007-04

Completion

2007-04

Drugs

Indications