drugset / Trial / NCT00260260
OXY-1: The Pharmacogenetics of Oxycodone Analgesia in Postoperative Pain
Non-randomizedSingle-groupOpen-labelTreatment
Summary
Patients undergoing surgery (thyroidectomy and hysterectomy) will postoperatively receive oxycodone intravenously (IV) as pain management with morphine as an escape medicine, if there is insufficient pain relief with oxycodone. Patients' pain and side effects will be registered and after 24 hours they will answer a questionnaire. All included patients will be genotyped accordingly to CYP2D6 and relevant single nucleotide polymorphisms (SNPs), and measures of plasma levels of oxycodone will be performed.
Timeline
- Start
- 2005-06
- Primary completion
- 2007-12
- Completion
- 2007-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oxycodone | Other / unclassified | 2 mg | Intravenous |
Indications
No indication recorded.