drugset / Trial / NCT00270140
A Study to Evaluate the Safety and Effectiveness of Epoetin Alfa Versus Placebo in Facilitating the Presurgical Collection of Blood to be Used for Self-donation During Surgery on the Spine, Hip, or Knee.
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to evaluate the safety and effectiveness of epoetin alfa at doses of 150, 300, or 600 units per kilogram of body weight versus placebo in facilitating presurgical collection of blood for self-donation during surgery of the knee, hip or spine. Epoetin alfa is a genetically engineered protein that stimulates red blood cell production.
Timeline
- Start
- 1989-09
- Primary completion
- —
- Completion
- 1991-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | epoetin alfa | Protein / enzyme biologic | 150 iu/kg | Intravenous |
| Subject | epoetin alfa | Protein / enzyme biologic | 300 iu/kg | Intravenous |
| Subject | epoetin alfa | Protein / enzyme biologic | 600 iu/kg | Intravenous |