COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension

Summary

This study was designed to determine whether treatment with COREG MR is more effective at maintaining a better lipid profile than treatment with TOPROL-XL for hypertension.

Timeline

Start

2006-01-05

Primary completion

2007-12-01

Completion

2007-12-28

Outcome

Mixed primary results

registry analysis (superiority or other test); Coreg CR vs Toprol XL; p = 0.0141; Median Difference (Net) -8.026 (95% CI -15.35 to -0.67); ANCOVA NCT00273052 ↗

registry NUMBER Coreg CR: 2.65 mg/dL NUMBER Toprol XL: 10.39 mg/dL NCT00273052 ↗

registry analysis (superiority or other test); Coreg CR vs Toprol XL; p = 0.6068; Mean Difference (Net) 0.7 (95% CI -2.4 to 3.9); ANCOVA NCT00273052 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Carvedilol	Other / unclassified	—	—
Comparator	Metoprolol	Other / unclassified	—	—

Indications