drugset / Trial / NCT00274599

PROBE Investigation of the Safety & Efficacy of Telmisartan (Micardis®) vs Ramipril (Altace®) Using ABPM in HTN

NCT00274599

Phase 4 Completed 812 enrolled Boehringer Ingelheim
RandomizedParallel-groupOpen-labelTreatment

Summary

Demonstrate that telmisartan 80mg was at least as effective and possibly superior to ramipril 5mg \& 10mg in lowering mean ambulatory DBP and SBP during the last 6 hrs of the 24-hr dosing interval in mild-to-moderate hypertensives at the end of 8 and 14 week treatment phases.

Timeline

Start
2002-10-09
Primary completion
2003-11-30
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Ramipril Small molecule 2.5 mg
Subject Ramipril Small molecule 5 mg
Subject Ramipril Small molecule 10 mg
Subject Telmisartan Other / unclassified 40 mg
Subject Telmisartan Other / unclassified 80 mg

Indications