drugset / Trial / NCT00274599
PROBE Investigation of the Safety & Efficacy of Telmisartan (Micardis®) vs Ramipril (Altace®) Using ABPM in HTN
RandomizedParallel-groupOpen-labelTreatment
Summary
Demonstrate that telmisartan 80mg was at least as effective and possibly superior to ramipril 5mg \& 10mg in lowering mean ambulatory DBP and SBP during the last 6 hrs of the 24-hr dosing interval in mild-to-moderate hypertensives at the end of 8 and 14 week treatment phases.
Timeline
- Start
- 2002-10-09
- Primary completion
- 2003-11-30
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ramipril | Small molecule | 2.5 mg | — |
| Subject | Ramipril | Small molecule | 5 mg | — |
| Subject | Ramipril | Small molecule | 10 mg | — |
| Subject | Telmisartan | Other / unclassified | 40 mg | — |
| Subject | Telmisartan | Other / unclassified | 80 mg | — |