A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints

Phase 4 Completed 2878 enrolled Ipsen

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine whether Tanakan® is effective at slowing the progression from memory complaint to dementia of Alzheimer's type.

Timeline

Start: 2002-02
Primary completion: 2009-11
Completion: 2009-11

Outcome

Missed primary endpoint

paper Long-term use of standardised ginkgo biloba extract in this trial did not reduce the risk of progression to Alzheimer's disease compared with placebo. PMID 22959217 ↗

Publications

Vellas B, Coley N, Ousset PJ, Berrut G, Dartigues JF, Dubois B, Grandjean H, Pasquier F, Piette F, Robert P, Touchon J, Garnier P, Mathiex-Fortunet H, Andrieu S; GuidAge Study Group. Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial. Lancet Neurol. 2012 Oct;11(10):851-9. doi: 10.1016/S1474-4422(12)70206-5. Epub 2012 Sep 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ginkgo Biloba Extract	Traditional medicine (herbal / TCM)	120 mg	Oral