Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity

Phase 3 Completed 70 enrolled Lindner Center of HOPE GlaxoSmithKline · collab University of Cincinnati · collab

RandomizedSingle-groupTriple-blindTreatment

Summary

This research study is to evaluate the effectiveness, tolerability, and safety of lamotrigine therapy in the treatment of binge eating disorder associated with obesity. Lamotrigine has been approved by the Food and Drug Administration for the treatment of bipolar disorder, but has not been approved for use in the treatment of binge eating disorder with obesity.

Timeline

Start: 2006-03
Primary completion: 2009-01
Completion: 2009-01

Publications

Results Guerdjikova AI, McElroy SL, Welge JA, Nelson E, Keck PE, Hudson JI. Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. Int Clin Psychopharmacol. 2009 May;24(3):150-8. doi: 10.1097/YIC.0b013e328329c7b5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lamotrigine	Small molecule	25 mg	—
Subject	Lamotrigine	Small molecule	100 mg	—

Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity

Summary

Timeline

Publications

Drugs

Indications