drugset / Trial / NCT00278863

Capecitabine Versus S-1 in Elderly Advanced Gastric Cancer (AGC): Randomized Trial

NCT00278863

Phase 2 Completed 96 enrolled Asan Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

A significant proportion of advanced gastric cancer (AGC) occurs in individuals 65 years of age and older. In addition, patient delay in seeking care for symptoms results in diagnosis at a more advanced stage than that seen in younger individuals. However, clinical trials on gastric cancer rarely have been available to the elderly. Recently oral 5-FU pro-drugs, which have been reported to have clinically significant response rates and survival with mild or negligible toxicities, have been widely used for the patients with AGC. However, few studies have been conducted in elderly patients.

Timeline

Start
2004-11
Primary completion
2007-01
Completion
2007-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Capecitabine Small molecule Oral
Comparator S-1 Small molecule Oral

Indications