Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy

Phase 3 Completed 660 enrolled Viatris Inc.

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to assess whether Lyrica is a safe and effective treatment for partial epilepsy in comparison with an established treatment, Lamictal.

Timeline

Start: 2006-08
Primary completion: 2009-12
Completion: 2010-04

Publications

Kwan P, Brodie MJ, Kalviainen R, Yurkewicz L, Weaver J, Knapp LE. Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial. Lancet Neurol. 2011 Oct;10(10):881-90. doi: 10.1016/S1474-4422(11)70154-5. Epub 2011 Aug 31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Lamotrigine	Small molecule	100 mg	Oral
Comparator	Lamotrigine	Small molecule	500 mg	Oral
Subject	Pregabalin	Small molecule	150 mg	Oral
Subject	Pregabalin	Small molecule	600 mg	Oral

Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy

Summary

Timeline

Publications

Drugs

Indications