Leflunomide in Rheumatoid Arthritis

Summary

Study objectives: * To provide more insight on the modulation of inflammation and matrix degrading factors in serum and urine by leflunomide in early , active patients with RA and to validate the sensitivity of DEMRI (Dynamic Enhanced Magnetic Resonance Imaging) in detecting inflammatory changes in active RA in response to treatment with leflunomide * Effect of leflunomide therapy on physical function improvement and Quality of life

Timeline

Start

2004-04

Primary completion

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Completion

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Drugs

Indications