drugset

drugset / Trial / NCT00281762

Urinary Aquaporin 2 Excretion After NSAID in Fasting Healthy Human

NCT00281762 ↗

Phase 4 Completed 20 enrolled Regional Hospital Holstebro

RandomizedCrossoverDouble-blind

Summary

We wanted to test the hypothesis that prostaglandin inhibition reduces the down regulation of u-AQP-2 induced by fasting

Timeline

Start: —
Primary completion: 2007-01
Completion: 2007-01

Publications

Lauridsen TG, Vase H, Starklint J, Graffe CC, Bech JN, Nielsen S, Pedersen EB. Increased renal sodium absorption by inhibition of prostaglandin synthesis during fasting in healthy man. A possible role of the epithelial sodium channels. BMC Nephrol. 2010 Oct 28;11:28. doi: 10.1186/1471-2369-11-28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ibuprofen	Small molecule	600 mg	—

Indications

No indication recorded.