drugset

drugset / Trial / NCT00283283

Comparison of Full-dose Flu Vaccine to Half-dose Flu Vaccine

NCT00283283 ↗

Phase 2 Completed 1316 enrolled U.S. Army Medical Research and Development Command Centers for Disease Control and Prevention · collab U.S. Air Force Office of the Surgeon General · collab Uniformed Services University of the Health Sciences · collab United States Army Medical Materiel Development Activity · collab Walter Reed Army Institute of Research (WRAIR) · collab Walter Reed Army Medical Center · collab

RandomizedParallel-groupSingle-blindPrevention

Summary

This study compared full-dose Flu vaccine to half-dose Flu-vaccine during the 2004-2005 flu season.

Timeline

Start: 2004-11
Primary completion: 2004-11
Completion: 2006-05

Publications

Results Engler RJ, Nelson MR, Klote MM, VanRaden MJ, Huang CY, Cox NJ, Klimov A, Keitel WA, Nichol KL, Carr WW, Treanor JJ; Walter Reed Health Care System Influenza Vaccine Consortium. Half- vs full-dose trivalent inactivated influenza vaccine (2004-2005): age, dose, and sex effects on immune responses. Arch Intern Med. 2008 Dec 8;168(22):2405-14. doi: 10.1001/archinternmed.2008.513.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Influenza Virus Vaccine	Vaccine	7.5 ug	Intramuscular
Subject	Influenza Virus Vaccine	Vaccine	15 ug	Intramuscular
Subject	Influenza Virus Vaccine	Vaccine	0.25 ml	Intramuscular
Subject	Influenza Virus Vaccine	Vaccine	0.5 ml	Intramuscular

Indications