Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes

Summary

The primary purpose is to determine if patients scheduled to receive prescription corticosteroid therapy for inflammatory illnesses who are given either memantine or riluzole pretreatment will show lesser declarative memory impairment than those receiving placebo. The exploratory purpose is to determine if patients scheduled to receive prescription corticosteroid therapy for inflammatory illnesses who are given memantine or riluzole pretreatment will show a smaller increase in manic/hypomanic symptom severity than those receiving placebo.

Timeline

Start

2005-11

Primary completion

2007-04

Completion

2007-04

Drugs

Indications

No indication recorded.