Salvage: Postconditioning With Adenosine for STEMI

Summary

Investigate the effect of selective intracoronary administration of adenosine on myocardial salvage and microvascular integrity in the setting of acute myocardial infarction.

Timeline

Start

2006-01

Primary completion

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Completion

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Outcome

Missed primary endpoint

paper No significant difference in MSI was found between adenosine- and placebo-treated patients PMID 21196444 ↗

Publications

• Desmet W, Bogaert J, Dubois C, Sinnaeve P, Adriaenssens T, Pappas C, Ganame J, Dymarkowski S, Janssens S, Belmans A, Van de Werf F. High-dose intracoronary adenosine for myocardial salvage in patients with acute ST-segment elevation myocardial infarction. Eur Heart J. 2011 Apr;32(7):867-77. doi: 10.1093/eurheartj/ehq492. Epub 2010 Dec 31.

Drugs

Indications