Effect of Rosiglitazone

Completed 12 enrolled University Hospital, Montpellier

RandomizedCrossoverDouble-blindTreatment

Summary

To evaluate : * acute effects of a single dose of 8 mg rosiglitazone (therapeutic dose) * on insulin secretion and * insulin sensitivity in 12 healthy male subjects.

Timeline

Start: 2004-06
Primary completion: —
Completion: 2004-11

Publications

Farret A, Chevassus H, Roux B, Petit P, Galtier F. Direct rosiglitazone-induced modifications in insulin secretion, action and clearance: a single-dose hyperglycaemic clamp study. Diabetologia. 2007 Jul;50(7):1384-7. doi: 10.1007/s00125-007-0682-4. Epub 2007 May 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Rosiglitazone	Small molecule	8 mg	Oral

Indications

No indication recorded.