Assessment of Bupropion on Cognitive Function and Behaviour in Healthy Volunteers

Completed 12 enrolled University Hospital, Montpellier

RandomizedCrossoverDouble-blindTreatment

Summary

To evaluate the effects of a 14-day repeated dose of 150 mg bupropion (therapeutic dose) on cognitive and executive functions, behaviour and subjective feelings, after sleep deprivation in 12 healthy male subjects.

Timeline

Start: 2004-11
Primary completion: —
Completion: 2006-02

Publications

Chevassus H, Farret A, Gagnol JP, Poncon CA, Costa F, Roux C, Galtier F, Petit P. Psychological and physiological effects of bupropion compared to methylphenidate after prolonged administration in healthy volunteers (NCT00285155). Eur J Clin Pharmacol. 2013 Apr;69(4):779-87. doi: 10.1007/s00228-012-1418-z. Epub 2012 Oct 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupropion	Small molecule	300 mg	—

Indications

No indication recorded.