drugset / Trial / NCT00291772
Continuous Subcutaneous Infusion of Pramlintide and Insulin
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to see if giving the study drug in a slow and steady dose will lower blood sugars during the meal and after-meal time.
Timeline
- Start
- 2006-01
- Primary completion
- 2007-11
- Completion
- 2007-11
Publications
- Results Heptulla RA, Rodriguez LM, Bomgaars L, Haymond MW. The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes. Diabetes. 2005 Apr;54(4):1100-7. doi: 10.2337/diabetes.54.4.1100.
- Heptulla RA, Rodriguez LM, Mason KJ, Haymond MW. Twenty-four-hour simultaneous subcutaneous Basal-bolus administration of insulin and amylin in adolescents with type 1 diabetes decreases postprandial hyperglycemia. J Clin Endocrinol Metab. 2009 May;94(5):1608-11. doi: 10.1210/jc.2008-2580. Epub 2009 Feb 3.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pramlintide | Peptide | 30 ug | Subcutaneous |
| Subject | Pramlintide | Peptide | 45 ug | Subcutaneous |