Safety and Efficacy Study of the Effect of Etanercept in Hemodialysis Patients

Phase 2 Terminated 10 enrolled Kaysen, George A., M.D., Ph.D. Amgen · collab Dialysis Clinic, Inc. · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

Etanercept is a novel anti-inflammatory agent currently used in patients with rheumatoid arthritis. We are examining whether Etanercept is effective in improving the nutritional status of hemodialysis patients as a consequence of its ability to decrease inflammation.

Timeline

Start: 2005-01
Primary completion: 2008-03
Completion: 2010-06

Publications

Results Don BR, Kim K, Li J, Dwyer T, Alexander F, Kaysen GA. The effect of etanercept on suppression of the systemic inflammatory response in chronic hemodialysis patients. Clin Nephrol. 2010 Jun;73(6):431-8. doi: 10.5414/cnp73431.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Etanercept	Protein / enzyme biologic	25 mg	Subcutaneous

Safety and Efficacy Study of the Effect of Etanercept in Hemodialysis Patients

Summary

Timeline

Publications

Drugs

Indications