drugset / Trial / NCT00298012

Methotrexate in the Treatment of Axial Spondyloarthritis

NCT00298012

RandomizedParallel-groupDouble-blindTreatment

Summary

The goal of this study is to evaluate the efficacy of oral methotrexate for the treatment of active axial spondyloarthritis (early ankylosing spondylitis or spondyloarthritis with sacroiliitis). Efficacy will be measured by reduction in the signs and symptoms of active spondyloarthritis including effects on back pain and stiffness, range of motion in the spine, physical function, quality of life and incidence of arthritis, enthesitis and anterior uveitis.

Timeline

Start
2006-03
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Methotrexate Small molecule 15 mg Oral
Subject Methotrexate Small molecule 20 mg Oral