drugset / Trial / NCT00299780
Safety Study of Parathyroid Hormone in Patients Needing Additional Stem Cell Mobilization.
Phase 1
Completed
12 enrolled
Massachusetts General Hospital
Beth Israel Deaconess Medical Center · collabDana-Farber Cancer Institute · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the safety of parathyroid hormone in combination with G-CSF when used as a stem cell mobilization regimen for patients who fail to mobilize sufficient progenitor stem cells after one or two attempts.
Timeline
- Start
- 2004-07
- Primary completion
- —
- Completion
- 2007-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Parathyroid Hormone | Protein / enzyme biologic | 10 ug | — |
| Subject | Parathyroid Hormone | Protein / enzyme biologic | 40 ug | — |
| Subject | Parathyroid Hormone | Protein / enzyme biologic | 60 ug | — |
| Subject | Parathyroid Hormone | Protein / enzyme biologic | 80 ug | — |
| Background | G-CSF | Unknown | 10 ug/kg | — |