Theophylline in Chronic Obstructive Pulmonary Disease

Summary

This will be a prospective randomized double-blinded parallel group clinical trial evaluating the short-term effects of theophylline therapy on exercise duration and lung function in patients with chronic obstructive pulmonary disease already receiving both tiotropium and a long-acting beta-agonist (salmeterol or formoterol).

Timeline

Start

2006-10

Primary completion

2010-05

Completion

2010-05

Publications

• Results Voduc N, Alvarez GG, Amjadi K, Tessier C, Sabri E, Aaron SD. Effect of theophylline on exercise capacity in COPD patients treated with combination long-acting bronchodilator therapy: a pilot study. Int J Chron Obstruct Pulmon Dis. 2012;7:245-52. doi: 10.2147/COPD.S29990. Epub 2012 Mar 29.

Drugs

Indications