drugset / Trial / NCT00300521
Liver Transplantation With ADV-TK Gene Therapy Improves Survival in Patients With Advanced Hepatocellular Carcinoma
Phase 2
Completed
40 enrolled
Beijing Chao Yang Hospital
The No.180 Hospital of People's Liberation Army · collabTongji University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Previous rather poor results in liver transplantation (LT) of patients with advanced hepatocellular carcinoma (HCC) have made the application of LT very limited in treatment of HCC. The advantages of ADV-TK gene therapy highlight its potentiality as adjuvant treatment for HCC patients after LT. We reported here the improved outcome of LT with combined treatment of ADV-TK gene therapy in patients with intermediate or advanced HCC.
Timeline
- Start
- 2000-09
- Primary completion
- —
- Completion
- 2005-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | aglatimagene besadenovec | Unknown | — | — |