drugset / Trial / NCT00301106
Biological Therapy in Treating Women With Breast Cancer That Has Spread to the Liver
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Biological therapy using a gene-modified virus that can make interleukin-12 may help the body build an effective immune response to kill tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of a gene-modified virus that can make interleukin-12 in treating women with breast cancer that has spread to the liver.
Timeline
- Start
- 2005-10
- Primary completion
- 2008-08
- Completion
- 2008-08
Outcome
Outcome not reported
Stopped: “protocol underwent significant revisions, decision made to terminate study and open as new study listed NCT00849459”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adv.RSV-hIL12 | Unknown | 1e+10 vg | Other |
| Subject | Adv.RSV-hIL12 | Unknown | 1e+13 vg | Other |
| Subject | Adv.RSV-hIL12 | Unknown | 2e+13 vg | Other |
| Subject | Adv.RSV-hIL12 | Unknown | 3e+13 vg | Other |