drugset / Trial / NCT00301795

Rituximab and Oblimersen in Treating Patients With Stage II, Stage III, or Stage IV Follicular Non-Hodgkin's Lymphoma

NCT00301795

Phase 2 Terminated 52 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Oblimersen may help rituximab work better by making cancer cells more sensitive to the drug. This phase II trial is studying how well giving rituximab together with oblimersen works in treating patients with stage II, stage III, or stage IV follicular non-Hodgkin's lymphoma

Timeline

Start
2006-03
Primary completion
2007-11
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Rituximab Monoclonal antibody Intravenous
Subject oblimersen sodium Antisense oligonucleotide Intravenous