drugset / Trial / NCT00302549
To Compare the Efficacy and Safety of FK506 vs IVC in the Treatment of Class III-IV LN
RandomizedParallel-groupOpen-labelTreatment
Summary
1. To compare the efficacy of FK506 vs intravenous cyclophosphamide pulses in the treatment of class III-IV LN. 2. To compare the safety and tolerability of FK506 vs intravenous cyclophosphamide pulses in the treatment of class III-IV LN. 3. To explore the dosing of FK506 and its effective range of blood concentration.
Timeline
- Start
- 2004-05
- Primary completion
- 2005-05
- Completion
- 2006-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tacrolimus | Small molecule | 0.1 mg/kg | — |