A Study of P38 Inhibitor (4) Monotherapy in Patients With Active Rheumatoid Arthritis

Summary

This 4 arm study will compare the safety and efficacy, with regard to reduction of signs and symptoms, of P38 Inhibitor (4) (50, 150 or 300mg po qd) monotherapy versus methotrexate monotherapy in adult patients with active rheumatoid arthritis. Patients will be randomized to receive one of 3 doses of P38 Inhibitor (4) or methotrexate. The anticipated time on study treatment is \<3 months, and the target sample size is 100-500 individuals.

Timeline

Start

2006-04

Primary completion

2007-12

Completion

2007-12

Drugs

Indications