drugset / Trial / NCT00309517
Randomized Study on Neoadjuvant Radio-Chemotherapy in Rectal Carcinoma Dukes B and C
RandomizedParallel-groupOpen-labelTreatment
Summary
This clinical investigation examined the influence of preoperative radiotherapy in combination with postoperative 5-fluorouracil + leucovorin chemotherapy vs. 5-fluorouracil + leucovorin + MAb 17-1A chemo-immunotherapy on patients' local recurrence rate and overall survival time following surgery for rectal carcinoma Dukes B or C (T2-4, N0-3, M0).
Timeline
- Start
- 1997-07
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | edrecolomab | Monoclonal antibody | — | — |
| Background | Fluourouracil | Unknown | — | — |
| Background | Leucovorin | Small molecule | — | — |