drugset / Trial / NCT00310024

Vorinostat and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT00310024

Phase 1 Completed 40 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects and best dose of vorinostat when given together with bortezomib in treating patients with relapsed or refractory multiple myeloma. Vorinostat and bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving vorinostat together with bortezomib may kill more cancer cells

Timeline

Start
2005-11
Primary completion
2008-02
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Vorinostat Small molecule Oral
Background Bortezomib Small molecule Intravenous

Indications