Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

Completed 69 enrolled Virginia Commonwealth University University of Louisville · collab

Non-randomizedSingle-groupOpen-labelDiagnostic

Summary

The purpose of this research study is to determine the effect of chronic nighttime low oxygen saturations on selected body systems (liver) that break down drugs in children with obstructive sleep apnea syndrome (OSAS).

Timeline

Start: 2003-01
Primary completion: 2006-02
Completion: 2006-02

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Caffeine	Small molecule	—	—
Subject	Dextromethorphan	Unknown	0.5 mg/kg	—

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

Summary

Timeline

Drugs

Indications