drugset / Trial / NCT00311610
Liposomal SN-38 in Treating Patients With Metastatic Colorectal Cancer
Phase 2
Completed
30 enrolled
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI) · collab
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy, such as liposomal SN-38, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well liposomal SN-38 works in treating patients with metastatic colorectal cancer.
Timeline
- Start
- 2006-01
- Primary completion
- 2007-01
- Completion
- 2010-06
Publications
- Results Ocean AJ, Niedzwiecki D, Atkins JN, et al.: LE-SN38 for metastatic colorectal cancer after progression on oxaliplatin: results of CALGB 80402. [Abstract] J Clin Oncol 26 (Suppl 15): A-4109, 2008.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 7-ethyl-10-hydroxy Camptothecin | Small molecule | 38 mg/m2 | Intravenous |