drugset / Trial / NCT00311740

A Study of VAH631 in Patients With Essential Hypertension (Factorial Study)

NCT00311740

Phase 3 Completed 582 enrolled Novartis
RandomizedFactorialDouble-blindTreatment

Summary

The purpose of this study is to compare the effect of the fixed combination of valsartan+hydrochlorothiazide (HCTZ) on blood pressure reduction with valsartan and HCTZ alone and whether the combination treatments are safe and well tolerated. The study aims to establish a dose response relationship for both monotherapies and the combinations. This study is being conducted in Japan.

Timeline

Start
2006-03
Primary completion
2006-09
Completion
2006-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydrochlorothiazide Unknown 6.25 mg
Subject Hydrochlorothiazide Unknown 12.5 mg
Subject Valsartan Small molecule 40 mg
Subject Valsartan Small molecule 80 mg

Indications