drugset / Trial / NCT00312507

Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration

NCT00312507

Phase 3 Unknown 20 enrolled The Hospital for Sick Children
RandomizedParallel-groupDouble-blindTreatment

Summary

The objective of this pilot study is to examine the feasibility and safety of performing a larger trial to assess outcomes following treatment of meconium aspiration syndrome with surfactant lavage compared to bolus surfactant. Specifically, we will determine if surfactant lavage results in a more rapid improvement in physiologic outcomes (e.g. pulmonary compliance), as well as clinical outcomes (e.g. length of time on mechanical ventilation).

Timeline

Start
2006-04
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Bovine Lipid Extract Surfactant Unknown Other