drugset / Trial / NCT00313521

Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors

NCT00313521

Phase 2 Unknown 30 enrolled Children's Cancer and Leukaemia Group
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving chemotherapy and radiation therapy after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well thiotepa works together with radiation therapy in treating young patients with newly diagnosed malignant brain tumors.

Timeline

Start
1995-06
Primary completion
1997-11
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Thiotepa Other / unclassified Intravenous