drugset / Trial / NCT00313547
High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to compare the impact of two blood pressure lowering treatments (high dose quinapril versus low dose quinapril plus amlodipine) on variations in heart rate over 24 hours.
Timeline
- Start
- 2006-04
- Primary completion
- 2007-04
- Completion
- 2008-03
Outcome
Outcome not reported
Stopped (Enrollment): “Very difficult to recruit patients/slow recruitment(2 patients in nearly 2 years).”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amlodipine | Other / unclassified | 5 mg | — |
| Subject | Quinapril | Small molecule | 10 mg | — |
| Subject | Quinapril | Small molecule | 40 mg | — |