MAST - Magnesium for Sickle Cell Acute Crisis in Children

Phase 3 Completed 120 enrolled The Hospital for Sick Children The Physicians' Services Incorporated Foundation · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to determine if intravenous magnesium sulfate treatment is effective in reducing the length of stay and pain in children with sickle cell disease suffering an acute vaso-occlusive episode.

Timeline

Start: 2006-04
Primary completion: 2008-08
Completion: 2013-07

Publications

Goldman RD, Mounstephen W, Kirby-Allen M, Friedman JN. Intravenous magnesium sulfate for vaso-occlusive episodes in sickle cell disease. Pediatrics. 2013 Dec;132(6):e1634-41. doi: 10.1542/peds.2013-2065. Epub 2013 Nov 25.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Magnesium Sulfate	Other / unclassified	100 mg/kg	Intravenous

MAST - Magnesium for Sickle Cell Acute Crisis in Children

Summary

Timeline

Publications

Drugs

Indications