drugset / Trial / NCT00322218

Study Comparing Zevalin Regimen With no Further Treatment in Patients With Diffuse Large B-cell Lymphoma.

NCT00322218

Phase 3 Terminated 68 enrolled Spectrum Pharmaceuticals, Inc Bayer · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This study treats patients with diffuse large B-cell lymphoma whose disease is in complete remission due to previous treatment with Cyclophosphamide Doxorubicin hydrochloride Vincristine Prednisolone- Rituximab (CHOP-R). Half of the patients received Zevalin and the other half receive no further anti-cancer treatment. The two patient groups compared to determine if Zevalin given after CHOP-R therapy provides greater benefits than receiving no additional anti-cancer therapy after CHOP-R.

Timeline

Start
2006-05
Primary completion
2008-12
Completion
2008-12

Drugs

EvaluationDrugModalityDoseRoute
Subject ibritumomab tiuxetan Monoclonal antibody 14.8 mbq/kg Intravenous
Subject ibritumomab tiuxetan Monoclonal antibody 185 mbq Intravenous
Background Rituximab Monoclonal antibody 250 mg/m2 Intravenous