drugset / Trial / NCT00329251
Study of the Influence of Vaccination in HIV Viral Load and Immunologic Responses Against HIV
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether an immunization schedule is beneficial to HIV-infected patients with CD4 recount over 500 cells/mm3 and undetectable viral load.
Timeline
- Start
- 2003-04
- Primary completion
- —
- Completion
- 2006-03
Publications
- Yek C, Gianella S, Plana M, Castro P, Scheffler K, Garcia F, Massanella M, Smith DM. Standard vaccines increase HIV-1 transcription during antiretroviral therapy. AIDS. 2016 Sep 24;30(15):2289-98. doi: 10.1097/QAD.0000000000001201.
- Castro P, Torres B, Lopez A, Gonzalez R, Vilella A, Nicolas JM, Gallart T, Pumarola T, Sanchez M, Leal M, Vallejo A, Bayas JM, Gatell JM, Plana M, Garcia F. Effects of different antigenic stimuli on thymic function and interleukin-7/CD127 system in patients with chronic HIV infection. J Acquir Immune Defic Syndr. 2014 Aug 15;66(5):466-72. doi: 10.1097/QAI.0000000000000207.
- Castro P, Plana M, Gonzalez R, Lopez A, Vilella A, Nicolas JM, Gallart T, Pumarola T, Bayas JM, Gatell JM, Garcia F. Influence of episodes of intermittent viremia ("blips") on immune responses and viral load rebound in successfully treated HIV-infected patients. AIDS Res Hum Retroviruses. 2013 Jan;29(1):68-76. doi: 10.1089/AID.2012.0145. Epub 2012 Dec 16.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hepatitis A | Vaccine | — | — |
| Subject | Hepatitis B | Vaccine | — | — |
| Subject | Measles-Mumps-Rubella | Unknown | — | — |
| Subject | Pneumococcal | Vaccine | — | — |
| Subject | SPUNOLEUCEL | Vaccine | — | — |
| Subject | Tetanus-diphteria | Unknown | — | — |
| Subject | Varicella | Vaccine | — | — |