drugset / Trial / NCT00333385

Summary

The aim of this trial was to compare the safety and efficacy of courses of tobramycin and ceftazidime, administered intravenously as either thrice daily short infusions or 24 h continuous infusion, in cystic fibrosis patients with acute exacerbation of chronic pulmonary PA infection. In conventional treatment regimens, ceftazidime is administered in the form of thrice daily short infusions, but pharmacodynamic considerations suggest that continuous infusion could be more effective.

Timeline

Start
2001-10
Primary completion
Completion
2004-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Ceftazidime Small molecule 200 mg/kg Intravenous