Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding

Summary

Whether beta-blockers or banding is the best therapy for primary prophylaxis of variceal bleeding is subject to debate. A randomized comparison between the two treatments was performed in candidates for liver transplantation. Patients with Child B and C cirrhosis with high risk varices and no previous variceal bleeding are randomized to propranolol or variceal bleeding. Primary end point is variceal bleeding

Timeline

Start

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Primary completion

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Completion

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Outcome

Outcome not reported

Stopped: “From the interim analysis resulted that more than 1000 patients were required to demonstrate a significant difference between the 2 treatments.”

Drugs

Indications