drugset / Trial / NCT00338390
Study to Evaluate Changes in CD4 on Replacing TDF With ABC or DDI+TDF With ABC+3TC
RandomizedParallel-groupOpen-labelTreatment
Summary
The study aims to ascertain whether the sole replacement of tenofovir with abacavir once a day improves the immunological response obtained with tenofovir + ddI or whether it is better to perform a double replacement of tenofovir and ddI with abacavir + lamivudine (joint formulation) in a single daily dose to achieve these objectives.
Timeline
- Start
- 2005-04
- Primary completion
- 2007-02
- Completion
- 2007-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Abacavir | Other / unclassified | 600 mg | — |
| Subject | Didanosine | Small molecule | 250 mg | — |
| Subject | Didanosine | Small molecule | 400 mg | — |
| Subject | Lamivudine | Other / unclassified | 300 mg | — |