drugset / Trial / NCT00338494
Dose Escalation Study of Clofarabine in Patients With Relapsed or Refractory Low Grade or Intermediate-Grade B-Cell Lymphoma
Non-randomizedSingle-groupOpen-labelTreatment
Summary
Clofarabine is a new chemotherapy drug which was FDA approved for the treatment of acute lymphocytic leukemia in children. This study is being done to see if Clofarabine works in adult patients with B-cell types of lymphoma. This research is being done to develop new treatments for patients with lymphoma whose cancer has returned or resisted treatment with previous chemotherapy.
Timeline
- Start
- 2005-10
- Primary completion
- 2010-03
- Completion
- 2011-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clofarabine | Other / unclassified | 10 mg/m2 | — |
| Subject | Clofarabine | Other / unclassified | 15 mg/m2 | — |
| Subject | Clofarabine | Other / unclassified | 20 mg/m2 | — |
| Subject | Clofarabine | Other / unclassified | 30 mg/m2 | — |
| Subject | Clofarabine | Other / unclassified | 40 mg/m2 | — |