Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery

Summary

The purpose of this study is to directly compare the safety and efficacy of intra-thrombus alfimeprase 0.3 mg/kg with placebo in acute peripheral arterial occlusion (PAO) as measured by a 30 day open vascular free surgery rate.

Timeline

Start

2006-04

Primary completion

2007-03

Completion

2007-03

Outcome

Outcome not reported

Stopped: “Based upon preliminary safety and efficacy results from a similar study.”

Drugs

Indications