Effect of Brain Lesion Severity on Treatment Response in Late-Life Depression

Completed 131 enrolled Duke University National Institute of Mental Health (NIMH) · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study will determine the relationship between brain lesion severity, treatment response, and frontal lobe brain function in people with late-life depression (LLD).

Timeline

Start: 2001-08
Primary completion: 2006-03
Completion: 2006-03

Publications

Taylor WD, Kuchibhatla M, Payne ME, Macfall JR, Sheline YI, Krishnan KR, Doraiswamy PM. Frontal white matter anisotropy and antidepressant remission in late-life depression. PLoS One. 2008 Sep 24;3(9):e3267. doi: 10.1371/journal.pone.0003267.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sertraline	Small molecule	50 mg	—

Effect of Brain Lesion Severity on Treatment Response in Late-Life Depression

Summary

Timeline

Publications

Drugs

Indications