drugset / Trial / NCT00345150

Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls

NCT00345150 ↗

Phase 1 Completed 30 enrolled Regional Hospital Holstebro
RandomizedCrossoverSingle-blind

Summary

The study tests the hypothesis that systemic and renal nitric oxide synthesis is changed in essential hypertension by investigating the effects of a non selective nitric oxide inhibitor on renal hemodynamics and sodium excretion in patients with essential hypertension. The results are compared with a group of healthy subjects.

Timeline

Start
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Primary completion
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Completion
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Drugs

EvaluationDrugModalityDoseRoute
Subject Ng-monomethyl-L-arginine (drug) Unknown — —

Indications