drugset / Trial / NCT00348556

Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure

NCT00348556 ↗

Phase 1/2 Terminated 4 enrolled Horng Chen FlowMedica, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

The objective of this study is to determine the safety and effectiveness of intrarenal administration of brain natriuretic peptide (BNP) in improving renal function as measured by glomerular filtration rate (GFR) and sodium excretion in patients hospitalized with acute congestive heart failure (CHF) and deterioration of kidney function (cardiorenal syndrome).

Timeline

Start
2005-12
Primary completion
2010-03
Completion
2010-03

Outcome

Outcome not reported

Stopped (Business): “Company providing catheter bought out, funding and supplies terminated”

Drugs

EvaluationDrugModalityDoseRoute
Subject Nesiritide Protein / enzyme biologic 0.03 ug/kg Intravenous

Indications