The Effect of High Dose Vitamin C in Burn Patients

Withdrawn United States Army Institute of Surgical Research University of Miami · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to see if intravenous Vitamin C will decrease the amount of IV fluids needed following burn injury in the first 48 hours.

Timeline

Start: 2006-07
Primary completion: 2008-03
Completion: 2008-03

Outcome

Outcome not reported

Stopped: “Inadequate resources to submit for approval”

Publications

Background Matsuda T, Tanaka H, Yuasa H, Forrest R, Matsuda H, Hanumadass M, Reyes H. The effects of high-dose vitamin C therapy on postburn lipid peroxidation. J Burn Care Rehabil. 1993 Nov-Dec;14(6):624-9. doi: 10.1097/00004630-199311000-00007.
Background Tanaka H, Matsuda T, Miyagantani Y, Yukioka T, Matsuda H, Shimazaki S. Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg. 2000 Mar;135(3):326-31. doi: 10.1001/archsurg.135.3.326.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Vitamin C	Other / unclassified	—	Intravenous

Indications

No indication recorded.