drugset / Trial / NCT00355082
Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial Epilepsy
RandomizedParallel-groupDouble-blindTreatment
Summary
This study is being conducted to determine the effectiveness of a lower monotherapy dose of lamotrigine than that currently approved.
Timeline
- Start
- 2006-05
- Primary completion
- 2008-11
- Completion
- 2008-11
Publications
- Background French JA, Hammer AE, Vuong A, Messenheimer JA. Analysis of three lamotrigine extended-release clinical trials: comparison of pragmatic ITT and LOCF methodologies. Epilepsy Res. 2012 Aug;101(1-2):141-7. doi: 10.1016/j.eplepsyres.2012.03.015. Epub 2012 Apr 10.
- Background French JA, Temkin NR, Shneker BF, Hammer AE, Caldwell PT, Messenheimer JA. Lamotrigine XR conversion to monotherapy: first study using a historical control group. Neurotherapeutics. 2012 Jan;9(1):176-84. doi: 10.1007/s13311-011-0088-3.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lamotrigine | Small molecule | 250 mg | — |
| Subject | Lamotrigine | Small molecule | 300 mg | — |